表观分布容积为0.15～0.31/kg、蛋白质结合率为 30～4C％。
The apparent volume of distribution is 0.15～0.31／kg and protein binding 30～40％.
表观分布容积和血浆非结合分数是药物分布中用得最广的参数。
The apparent volume of distribution and the unbound fraction in plasma are the most widely used parameters for drug distribution.
一般而言，表观分布容积决定初始剂量，总清除率决定维持剂量。
In general, the initial dose depends on the volume of distribution, and maintenance doses depend on clearance.
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