血清总铁结合力(TIBC)是指能与100ml血清中全部转铁蛋白结合的最大铁量称为总铁结合力。正常人血循环中的转铁蛋白约30%被饱和。通常用测定总铁结合力的方法来间接测定转铁蛋白的水平。由于血清中还有极少量的铁与其他的蛋白质结合,故所测得的TIBC结果不能完全准确反映转铁蛋白的含量。TIBC与血清铁同时检测,其临床意义更大。
目的建立一种血清总铁结合力(TIBC)的直接比色测定法,不需去除饱和血清转铁蛋白后多余的铁。
Objective to establish a method for measurement of total iron binding capacity (TIBC) in serum without separation of the unbound excess iron after saturating serum transferrin.
红细胞三个平均值低,红细胞分布宽度(RDW)增高,血清铁和铁蛋白降低,总铁结合力增高。
Three mean values evaluating red blood cells decreased, the red cell distribution width (RDW) increased, serum iron and ferritin were lower, total iron binding capacity was higher.
慢性疾病性贫血是一类以血清铁低、总铁结合力低、贮存铁增加为特征的贫血。
Anemia of chronic disease is an anemia characterized by reduced serum iron concentrations, total iron binding capacity, whereas iron stores are increased.
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