血栓机化即血栓形成后,从血管壁向血栓长入内皮细胞和纤维母细胞,随即形成肉芽组织,血小板的血小板生长因子可能起着促使肉芽组织生长的作用。肉芽组织伸入血栓,逐渐加以取代而发生机化。
...,已开始有内皮细胞、成纤维细胞和成肌纤维细胞从血管壁长入血栓并逐步取代血栓,这个进程称为血栓机化(thrombus organization);呈现新生血管使血流得以部份恢复称再通。
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After thrombus was removed by Fogarty balloon catheter in different time, the numbers of endothelial denudation and the depth of injured venous wall are significantly different (P<0.05) between the time before and after thrombus organization.4.
3.不同时相应用Fogarty球囊导管取栓后,静脉壁内皮细胞残留数量、静脉血管壁损伤的深度,在静脉血栓机化前后有显著性差异(P<0.05)。
参考来源 - 不同时相Fogarty球囊导管取栓对大鼠下腔静脉壁的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
右边的曾有血栓形成,血栓机化后再通,可以看到有三个内腔。
The coronary at the right is even worse with evidence for previous thrombosis with organization of the thrombus and recanalization such that there are three small lumens remaining.
肺血栓栓子粘附于肺动脉壁上,如果病人幸存的话,血栓将机化,大多数情况下将脱落。
This pulmonary embolus is adherent to the pulmonary arterial wall. If the patient survives, the thromboembolus will organize and, for the most part, be removed.
结论:静脉血栓早期机化阶段大鼠模型制作成功。
Conclusion: the DVT model in rats at the early stage of thrombus organization was successful.
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