目的：探索日本血吸虫单克隆抗独特型抗体NP30对血吸虫虫卵肉芽肿细胞凋亡的影响。
Objective:To study the effect of monoclonal anti-idiotypic antibody NP30 on apoptosis of egg granuloma cells in mice infected with Schistosoma japonicum.
组织内虫卵抗原和抗体的动态变化与组织内虫卵肉芽肿病变程度密切相关，表明血吸虫卵抗原是肝组织虫卵肉芽肿病变的致病因子。
The kinetics of the levels of egg antigen and antibody in liver tissue demonstrated a direct bearing on the formation of schistosome egg granulomas.
另外，NP30主动免疫对血吸虫病虫卵肉芽肿和肝纤维化有明显的负调节作用。
Moreover, NP30 plays a significant down-modulatory role to hepatic granuloma and fibrosis.
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