2007年一个研究小组发现，两种普通基因(EML4和ALK)和一个异常化基因的融合能形成肿瘤。
In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours.
这项实验发现大鼠的血液干细胞与小鼠的Purkinjie神经元相融合后，停止表达血细胞蛋白，转而表达大鼠神经元特异性基因产物。
This showed nuclei from rat blood stem cells that had fused to Purkinje cells in mice stop expressing blood cell proteins and begin to express rat neuron-specific gene products.
在回顾性复习这些病例的基础上，作者发现伴 ZC3H7B-BCOR 基因融合的 ESS 构成了高级别 ESS 一种新的亚型，并且该亚型与黏液样型平滑肌肉瘤在形态学上有显著的重叠。
On the basis of the review of these cases, we find that ESS with ZC3H7B-BCOR fusion constitutes a novel type of high-grade ESS and shares significant morphologic overlap with myxoid leiomyosarcoma.
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