从药物过敏试验、加药、给药间隔时间方面综述了抗生素临床应用中护士应重视的问题。

It reviewed the problems nurses should pay attention to in clinical application of antibiotics from aspects of drug sensitivity test, interval time of drug addition and administration.

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方法：将受试豚鼠分为试验组和对照组，分别外用贞红生发酊及对照药物，在规定时间内观察豚鼠皮肤的刺激性、过敏性反应。

Method: Subjects guinea pigs were divided into test group and control group, separately for external use and control of drug. At the time guinea pigs skin irritation, allergic reaction.

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鱼腥草蒸馏液中含有其他引起过敏反应的过敏原。体外过敏试验结果与动物试验结果一致，体外致敏模型可用于药物过敏原的筛选。

The results of in vitro allergy test are consistent with animal studies, in vitro sensitization model can be used in drug screening allergens.

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