本发明提供一类具有以右式结构式所示结构的新的具有抗肿瘤活性的能溶于水的喜树碱衍生物及其应用、以及包括该化合物的药物组合物。
This invention provides a new camptothecin derivative with anti-tumor activity and structure as the right formula dissolving in water, its application, and its drug combinations.
综述了喜树碱及其衍生物的小分子、大分子和轭合物前药的研究进展，为新型喜树碱前药的合理药物设计提供一定参考。
The recent progress in low molecular, high molecular and couplet prodrugs of CPTs was reviewed in classified manner, provide a reference for the design of prodrugs of CPTs.
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