因此，胰岛素抵抗是2型糖尿病致动脉粥样硬化的潜在病因。
Therefore, insulin resistance is believed to constitute the underlying cause of atherosclerosis in type 2 diabetes.
目的克隆、分离血管内皮细胞在致动脉粥样硬化因素作用下差异表达的基因，了解动脉粥样硬化发生的分子机制。
Objective to isolate and clone the differential expressed genes induced by atherogenic factors on vascular endothelium and to understand the molecular mechanism of atherosclerosis.
LDL受体介导的低密度脂蛋白胆固醇水平的升高是致动脉性粥样硬化的主要原因，与冠心病危险性的增加密切相关。
The LDL receptor defects cause the elevation LDLcholesterol in plasma. This is the main reason for atherosclerosis and is closely related to the risk of coronary heart disease (CHD).
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