目的:研究多发性骨髓瘤(MM)患者肿瘤冻融物致敏的树突细胞(DC)能否诱导特异性细胞毒t淋巴细胞(CTL)反应。
Objective: to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma (MM) patients.
结果骨髓瘤冻融物致敏DC诱导的自身T细胞对患者骨髓瘤细胞的杀伤率远大于非致敏dc。
Results Autologous t lymphocytes induced by DCs pulsed with myeloma lysates had stronger killing effect on myeloma cells than t lymphocytes induced by non myeloma antigen pulsed DC.
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