然后，他们又研究在不同细胞里缺乏PrP的老鼠们，以期找到哪个细胞是脱髓鞘作用发生的根源。

Then, they studied mice that lacked PrP in some cells but not in others to see which cells were behind the demyelination.

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虽然其确切的病因和发病机理尚不十分清楚，但许多研究表明免疫学因素在中枢神经系统炎性脱髓鞘病中起着关键性的作用。

Although the definite etiology and pathogenesis are not very clear up to now, many studies show that the immunological factors play a key role in the demyelinating disease of CNS.

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施万细胞很早就被看作用来治疗神经损伤和脱髓鞘紊乱性疾病，例如多器官硬化病，甚至脊髓损伤。

"Schwann cells have been proposed as a cell type for treatment of nerve injuries, demyelination disorders such as multiple sclerosis, and even spinal cord injury, " said Dr.

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