研究小组观察发现，血糖-胰岛素比率和定量胰岛素敏感性检测指数明显下降，而基线胰岛素和内环境稳态模型评估指数明显升高。

The team observed significant decreases in glucose-insulin ratio and quantitative insulin-sensitivity check index, and significant increases in baseline insulin and homeostasis model assessment.

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该组的餐后2小时血糖检测结果也显示了确诊前3年的剧烈增加，而HOMA胰岛素敏感性在确诊5年前就直线下降。

In this group, the 2-hour postload glucose measure also showed a rapid increase that started about 3 years before diagnosis, and HOMA insulin sensitivity fell sharply during 5 years before diagnosis.

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方法给予实验大鼠高脂饮食喂养12及20周，并检测其肥胖评定指标，胰岛素敏感性及血脂谱。

Method the experimental rats were given fat rich diet for 12 and 20 weeks, measured their Lee Index, insulin sensitivity and lipid profile.

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