目的探讨筛查胎儿唐氏综合征的临床意义。

Objective Screening for fetal Down syndrome clinical significance.

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孕11 - 13 + 6周胎儿颈项透明层(NT)厚度已经成为早孕期筛查唐氏综合征的重要指标。

In 11-13 + 6 weeks, fetal nuchal translucency (nt) thickness has become an important index of down's syndrome of early pregnancy screening.

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当假阳性率为5%时，单项母体血清PAPP-A、单项孕妇年龄、母体血清PAPP-A联合孕妇年龄及丈夫年龄筛查唐氏综合征胎儿的灵敏度分别为60%、50%、80%。

Maternal PAPP-A, maternal PAPP-A combined with maternal age and paternal age, and maternal age would respectively detect 60%, 80% and 50% of Down's syndrome fetuses with a false positive rate of 5%.

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