血管形成是实体肿瘤增殖和转移的关键步骤，这一过程依赖于内源性刺激因子和抑制因子之间的平衡。

Angiogenesis is the key step in tumors proliferation and metastasis, which depends on the net balance between endogenous stimulators and inhibitors.

youdao

TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。

TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.

youdao

肿瘤血管生成是肿瘤生长转移的关键步骤，是促血管生成因子和抑制因子作用失衡的结果。

Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis.

youdao