结论：具有血管生成拟态的双向分化恶性肿瘤恶性度高、血道转移早、临床预后差。
Conclusion: Tumors with vasculogenic mimicry have a high-grade malignancy, early blood metastasis and poor clinical prognosis.
肿瘤细胞表达基质金属蛋白酶类物质和勃附分子说明了恶性黑色素瘤组织存在血管生成拟态形成的物质基础。
TIMP, MMP-2,1C AM were secreted by the tumor cells can boost the adhere of tumor cells and matrix remold and turn into the substance base of vasculogenic mimicry .
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