由于该机制可影响特定抑癌基因的活性,因而与肿瘤形成密切相关。
This mechanism is particularly relevant in cancer since it can interfere with the activity of specific "suppressor" genes.
因此,探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。
Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.
虽然有事实证明一些微小rna能够起癌基因或者抑癌基因,但是其在肿瘤的侵袭和转移中的作用尚未有研究。
Although there is emerging evidence that some microRNAs can function as oncogenes or tumour suppressors, the role of microRNAs in mediating cancer metastasis remains unexplored.
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