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他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
一些变异的细胞快速生长,另一些则刺激附近的血管生长出新的毛细血管,其它的则使癌细胞进入血循环并生成新的肿瘤。
Some mutations spur rapid growth; others prod nearby blood vessels into sprouting new capillaries; still others send cancer cells out into the bloodstream, where they can seed new tumors.
肿瘤体积的缩小、循环肿瘤细胞数目的下降和患者症状的改善均支持这些研究结果。
These results are supported by evidence of tumour shrinkage on scans, drops in circulating tumor cell counts and improvements in symptoms.
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