肾脏纤维化是一种病理生理改变，是肾脏的功能由健康到损伤，再到损坏，直至功能丧失的渐进过程。
Conclusions TIMP-1 could promote age-related renal fibrosis through enhancing inflammation reaction by ICAM-1 upregulation.
结论TIMP-1通过上调ICAM-1、增强炎症,促进衰老相关肾脏纤维化。
参考来源 - 人TIMPThe prevention and cure to progression of kidney fibrosis has already been the focus of diabetic nephropathy research.
故防治肾脏纤维化的进展已成为糖尿病肾病研究的焦点。
参考来源 - 脂联素对高糖环境下人肾小管上皮细胞增殖及TGF·2,447,543篇论文数据，部分数据来源于NoteExpress
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