...肾小管细胞：ARF时有两种肾小管损伤的病理特征，即为小管破裂性损伤（tubulorrhexic lesion）和肾毒性损伤（nephrotoxic lesion）。前者表现为肾小管上皮细胞坏死、脱落，基底膜也被破坏。
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Conclusion Activation of neutrophils,especially the release of MPO in renal tissue in the early stage of acute renal failure plays an important role in acute nephrotoxicity induced by high-dose DDP in mice.
结论中性粒细胞的激活,特别是肾皮质中性粒细胞MPO的释放在大剂量DDP所致小鼠肾毒性损伤早期发挥重要作用。
参考来源 - 中性粒细胞在实验性小鼠肾毒性损伤中的变化及其意义·2,447,543篇论文数据，部分数据来源于NoteExpress
目的：研究p选择素在高胆固醇血症小鼠肾脏的表达，探讨脂质肾毒性损伤的机制。
Objective: to detect the expression of P-selectin in mice with hypercholesterolemia, and to explore the mechanism of toxic injury to the kidney induced by lipid.
研究硒对急性镉中毒性肾损伤的保护作用。
Protective effect of selenium on acute toxic renal damage caused by cadmium was studied.
结论桃核承气汤可以通过改善肾脏氧化损伤对庆大霉素肾毒性起到一定的治疗作用。
ConclusionTaohe Chengqi Decoction has some therapeutic effect on Gentamicin-induced kidney lesion through alleviating renal oxidation.
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