...形态发生蛋白-7在抗肾小管-间质纤维化中的作用 下载PDF阅读器 摘要： 肾小管-间质纤维化(renal tubulointerstitial fibrosis,RTF)是各种原因引起的慢性肾脏疾病进展为终末期肾病的共同途径,RTF特征是正常肾小管和肾间质结构被大量聚集...
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间质细胞增殖和凋亡失衡及细胞间质代谢失调也是造成肾小管间质纤维化的两个不可缺少的原因。
The imbalance of interstitial cell proliferation and apoptosis and the metabolic disorder of intercellular substance, are two essential factors for renal tubulointerstitial fibrosis.
结论雌激素可能通过抑制UUO大鼠肾小管上皮细胞表型转化而发挥延缓肾间质纤维化的作用。
Estrogen can prevent the development of interstitial fibrosis, the mechanism may with it restrain the tubular epithelial cell phenotype transdifferentiation in UUO rats.
P21可能参与肾小管间质纤维化的发病过程。
P21 may participate in the pathogenesis of renal tubule-interstitial fibrosis.
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