肾小管间质损伤(tubulointerstitial lesions，TIL)是影响IgAN预后的重要危险因素。肾活检是目前诊断IgAN、判别其TIL的重要手段。
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肾小管-间质损伤 Renal tubule-interstitium injury
患者肾小管间质损伤 tubulointerstitial lesion ; TIL
和肾小管间质损伤指数 tubulointerstitial index ; TII
与肾小管间质损伤指数 tubule interstitial score ; TIS
及肾小管间质损伤指数 tubulointerstitial injure index
After treating , in Matrine group the index of tubulointerstitial injury is lower than that in pathology group (p <0.
治疗后，苦参碱治疗的各组肾小管间质损伤指数低于病理对照组(p＜0.05)。
参考来源 - 苦参碱对腺嘌呤致大鼠肾间质纤维化的干预作用研究·2,447,543篇论文数据，部分数据来源于NoteExpress
结论TIMP - 1过表达可通过增强炎症加重肾小管间质损伤。
Conclusions Overexpression of TIMP-1 exacerbates renal tubulointerstitial injury by enhancing inflammation.
结果：肾小球系膜区FN与系膜细胞增生、肾小球损伤程度及肾小管间质损伤程度均呈正相关。
Results Positive correlations were found between the degree of FN in glomerular mesangium or basement membranes and glomerular lesion grading or tubulointerstitial lesion grading.
单变量分析表明，血清肌酐水平、肾小球和肾小管间质损伤的严重程度都与高尿酸血症显著相关。
Univariate analysis showed that the level of serum creatinine and the severity of glomerular and tubular interstitial injury were significantly related to hyperuricemia.
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