结论提示接触COE可引起肺通气功能减退和呼吸系统的损害，且随工龄延长有加重的趋势。

Conclusion the COE might cause lung ventilatory function impairment and lung damage tend to be aggravated with the elongation of the exposure time.

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结论吸烟影响肺通气功能，早期主要表现为小气道功能减退。

Conclusion Smoking could injure ventilatory function, and initial manifestations are hypofunction mainly in small airway.

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