结论血必净可明显抑制脂多糖诱导的急性肺损伤大鼠肺组织增强的HMGB1表达,减轻脂多糖诱导的大鼠肺损伤程度。
Xuebijing could attenuate the degree of acute lung injury in rats induced by LPS, which may be related to its inhibition of the HMGB1 protein expression in lung tissue.
结果染毒后小鼠脾、肝、肺、肾组织细胞DNA出现损伤,且损伤程度与染毒剂量具有一定相关性。
Results DNA of spleen, liver, lung and kidney cells was significantly damaged after exposure, and there were some correlation between exposure concentration and damage degree.
结论:银杏叶提取物能够通过保护肺组织细胞线粒体膜结构完整性来降低线粒体损伤程度,维持细胞正常的能量代谢。
CONCLUSION: EGb can decrease the injured degree of mitochondria and maintain lung cells energy metabolism by protecting the integrality of mitochondria membrane.
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