结果:①在生理条件下,银杏苦内酯B可缩短心室肌细胞动作电位时程(action potential duration,APD),但对AP其他参数无影响,银杏苦内酯B可增大IK,呈浓度依赖性,但对ICa-L无显著作用;②在缺血条...
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目的:研究自发性高血压大鼠(SHR)左心室肌细胞动作电位时程延长的膜离子流基础。
Objective: To study the membrane ionic basis of action potential prolongation of hypertrophied left ventricular myocytes in spontaneously hypertensive rats (SHR ).
方法应用全细胞膜片钳技术记录乌头碱对大鼠心肌细胞动作电位时程的作用,分别给予奎尼丁、维拉·帕米处理比较二者对动作电位时程的影响。
Methods Effects of quinidine and verapamil on the alteration of action potential duration induced by aconitine were studied by use of the whole cell patch clamp techniques in rat ventricular myocytes.
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