...毒携带者治疗可以采用目前治疗乙肝最有效的方法在科学检查的基础上进行辨病辨证具体分期分型,应用乙肝胆毒变异、耐药检测(YMDD),根据患者乙肝胆毒基因的个体差异、病毒的变异、乙肝感染的病情、病毒DNA的复制情况、是否合并有其他病毒感染以及免疫状态等各种...
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所有5例均有少见的耐药突变,这些突变一些耐药检测无法检出。
All had uncommon drug-resistance mutations that some resistance tests would miss.
结果与临床常规方法相比,耐药检测基因芯片鉴定指标的灵敏度均>96%,特异度均>98%;
Results The sensitivity of all identification indexes of DNA chip were higher than 96%, and all of their specificity were higher than 98%.
本文就HIV-1表型耐药定义、检测方法、存在优缺点及其与基因型耐药检测结果一致性等进行综述。
Definition, testing, advantage and disadvantage of phenotypic resistance assay of HIV-1 and its concordance with genotypic resistance assay were summarized in this paper.
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