脑缺血后，及时恢复缺血区脑组织的血液供应，尤其是缺血半暗带区的血液供应，对于缺血性脑血管病的治疗与预后意义重大。

To recover blood supply of brain tissue in ischemic region especially in ischemic penumbra in time, it will have great significance in treating and prognosis.

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目的：研究大鼠局灶性脑缺血不同缺血时间皮质半暗带和中心区淀粉样前体蛋白(APP)在转录水平表达规律。

Aim: To investigate the changes of amyloid precursor protein (APP) transcriptional level at different ischemic times in rats' ischemic penumbra and core of cortices.

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