瑞典神经病学专家卡尔 - 阿克塞尔·埃克波姆在1945年首次发现这种疾病，因此不宁腿综合征又被称为埃克波姆综合征（Ekbom syndrome）。

The condition was first described in 1945 by Swedish nerve specialist Karl-Axel Ekbom. As a result, RLS is sometimes known as Ekbom syndrome.

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最近，科学家发现，两种基因突变和不宁腿综合征（restless leg syndrome ，RLS）有关，遗传这种基因突变的人更容易发生不宁腿综合征。

People who inherited the mutations are much more likely to develop restless leg syndrome, the researchers report in the journal PLoS Genetics.

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