本给药系统在“漏槽”状态下测定释放速度，经短时间的较快释放后可维持长期的零级速度。

After a initial transient, "burst effect", the drug was released continuously from the device at a constant rate for a long period of time.

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近年来，SLN的口服和经皮给药逐渐受到重视，研究发现，口服经过SLN包裹后的药物能降低其血药浓度峰值，并延长药物作用时间。

Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.

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结果珍珠滴丸给药后可明显缩短大鼠口腔黏膜溃疡50%愈合时间。

Results The pearl drop pills can obviously shorten 50% concrescence time of rats oral ulcer.

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