FN剪切变异体在调节细胞基质,基质与基质间的相互作用,骨骼发育和四肢骨骼功能及其他方面起到很重要的作用。
FN splice variants play important roles in regulating cell-matrix and matrix-matrix interactions in skeletogenesis and skeletal function in limbs and other sites.
整合素是一类广泛存在于细胞表面的粘附分子,介导细胞—细胞及细胞—细胞外基质间的粘附及信息传导。
Integrin, a kind of adhesion molecule generally exists on the cell surface, mediates adhesion and information transmissions between cell-cell and between cell-extracellular matrix.
BMP分子可以诱导间充质细胞分化为软骨细胞,促进合成细胞外基质,抑制软骨细胞的终末分化。
BMP may induce mesenchymal cells to differentiate into chondrocytes, promote the synthesis of extracellular matrix and inhibit the terminal differentiation of chondrocytes.
Well, it's true that it's not stuck to plastic but it is stuck to other materials The other materials that it's stuck to include other cells that surround it and this complex matrix which surrounds all of the cells in our body called extracellular matrix and I'll get to that in just a few moments.
体内的细胞不会贴在塑料片上,但是它们会和别的材料黏联在一起,这些材料包括,细胞和周围细胞间的黏联,细胞同细胞外基质的黏联,我们身体中包围在细胞周围的物质,称为细胞外基质,后面我会详细讲到
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