目的:探讨焦炉工外周血淋巴细胞热应激蛋白70 (HSP70)表达水平及与外周血淋巴细胞遗传损伤之间关系及其意义。
Objective: To investigate the relationship between the expression of heat shock protein70 (HSP70) and genetic damage in coke oven workers and their functions.
不过,还有个悬而未决的问题:假定癌细胞内出现遗传损伤的情况,那么,哪种类型的损伤可以作为肿瘤存在的理想指标?
But it is an open question, given all the genetic damage in a cancer cell, as to which type of damage would be the best marker of a tumor's presence.
DNA修复对遗传信息的准确保存和确保细胞的正常功能是必需的,年龄和DNA损伤的关系一直存在疑问。
DNA repair is essential for the accurate preservation of genetic information and to ensure the healthy functioning of cells, and a connection between aging and DNA damage has long been suspected.
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