目的：研究高糖对正常人类系膜细胞（NHMC）增殖及金属蛋白酶2（MMP2）和金属蛋白酶9（MMP9）表达的影响及肝素对其的干预作用。
Objective: To investigate the effects of high glucose and heparin on the proliferation and expression of MMP2, MMP9 in normal human mesangial cells (NHMC).
结论：成功地建立了人乙酰肝素酶稳定表达细胞株，为其抑制剂的筛选及其功能的研究奠定了基础。
Conclusion: Heparanase stable expression cell lines have been successfully established, which could be of great benefits to the screening and function study of its inhibitors.
本文探讨乙酰肝素酶基因转染卵巢癌SKOV3细胞后对细胞生长、黏附、侵袭能力的影响。
This article evaluates the effect of heparanase gene on the proliferation, adhesion and invasion of human ovarian cancer cell line SKOV3 cells.
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