经磷酸化活化的丝裂原活化蛋白激酶,可参与多种细胞生命活动,如调节基因转录,诱导细胞凋亡、调节细胞周期等。
The MAPK which activated through phosphorylation involve several cell life activities, just like the control gene transcription, induce cell death, regulate cell circle and so on.
CD4 7是T细胞活化的共刺激因子,活化T细胞凋亡过程,诱导T细胞无反应性,加强TCR信号传导的效率;
CD47 induces costimulatory signals on activation of T cell, T cell apoptosis and T cell anergy and enhances the efficiency of TCR signaling;
结论P KC、TPK在T细胞活化、增殖及诱导肝癌细胞凋亡的信号转导中起重要作用。
Conclusion PKC and TPK play important role on the signal transduction in the activated and proliferating t cells and the induction of apoptosis of hepatoma cells.
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