肿瘤 | 生命奥秘 X-C趋化因子受体4（c-X-c chemokine receptor 4，CXCR4）阳性的HPC细胞和转移肿瘤细胞（metastatic tumour cells，MTC）相作用。HPC分泌出了一系列的转移前因子（pre-metastatic factors），比如肿瘤坏
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肿瘤 | 生命奥秘 X-C趋化因子受体4（c-X-c chemokine receptor 4，CXCR4）阳性的HPC细胞和转移肿瘤细胞（metastatic tumour cells，MTC）相作用。HPC分泌出了一系列的转移前因子（pre-metastatic factors），比如肿瘤坏
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肿瘤干细胞学说认为，肿瘤组织中也存在少量具有干细胞性质的肿瘤干细胞，肿瘤干细胞是肿瘤发生、转移和复发的关键。
The theory of cancer stem cell proposes that the tumor tissue has its own cancer stem cells in it and regards cancer stem cell as the key to regeneration, metastasis and recurrence.
有证据证明IGF - 2在许多肿瘤细胞中可使细胞增殖增加，抑制凋亡，增加局部浸润和转移。
There are evidences that IGF-2 increases cell proliferation, inhibits apoptosis and raises local infiltration and transfer in many tumor cells.
肿瘤干细胞是在实体肿瘤中发现的一个小的细胞亚群，其具有自我更新和分化、引发肿瘤并促进肿瘤生长、复发和转移的能力。
Cancer stem cells, a small subset of cells found in solid tumors, have the capacity to self-renew and differentiate, initiate tumors and drive tumor growth, recurrence and metastasis.
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