目的：研究视神经损伤后神经胶质细胞去分化的程度及相关分子的表达。

Objective: To investigate the dedifferentiation of glia cells and the expression of related molecules after optic nerve injury.

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利用血液去培育干细胞获得成功以后，朱敏设法诱导它们分化成三种细胞系：先是骨骼和软骨细胞，然后是肌细胞，再是神经元。

Using blood to nourish and grow the stem cells, Zhu managed to induce them to differentiate into three lineages: first bone and cartilage, then muscle, and then neuron.

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研究表明，组蛋白的乙酰化与去乙酰化状态，可作用于T、B细胞的发育、分化、成熟、分泌及表面因子的表达等多个方面。

Studies had shown that acetylation and deacetylation of histone are of certain value on t, B cell's development, differentiation, maturation, secretion and surface factor's expression etc.

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So far our ability to de-differentiate cells or find out how to do that is limited.

迄今为止,我们令细胞去分化的能力,和技术方法还相当有限

耶鲁公开课 - 生物医学工程探索课程节选

How we could take cells that are differentiated to some extent and make them de-differentiate, to go back in the process of differentiation so that they gain more potential.

我们如何把一些已经分化到,一定程度的细胞去分化,使其回到分化之前,重新获得更多的潜能

耶鲁公开课 - 生物医学工程探索课程节选

Well, it would be useful because if I could take cells from the skin, find stem cells in the skin and then de-differentiate them so that they were now capable of becoming liver, or brain, or things that they're not going to become in their normal site, then that could be a very powerful tool for medicine.

这是因为,如果我能取一些皮肤细胞,找一些皮肤干细胞,并将它们去分化,那它们就能分化成肝脏,大脑或其他一些,它们原本分化不出来的细胞,这可以成为一个医学利器

耶鲁公开课 - 生物医学工程探索课程节选