TRAIL分子有4个膜受体,其中包括,两个有完整的胞浆内段、能够介导凋亡信号、诱导细胞凋亡的死亡受体(death receptor, DR),即DR4、DR5;两个缺少完整的胞浆区、不能够转导凋亡信号的诱骗受体(decoy receptor...
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近年来对凋亡发生和调控机制的研究表明,细胞凋亡途径主要有两条:线粒体途径和死亡受体途径。
In recent years, studies of occurrence and regulation mechanism of apoptosis show that the two major apoptotic pathways are the mitochondrial and death receptor pathways.
结论:苦参碱能诱导C6胶质瘤细胞的凋亡,其机制与死亡受体途径和线粒体途径的众多基因有关。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
死亡受体通过细胞内信号传导途径可诱导细胞凋亡,与机体的生长、发育、病变和死亡有关。
Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death.
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