位于胞质溶胶、核基质中的受体称为细胞内受体(intracellular receptor)。 细胞内受体主要是同脂溶性的小信号分子相作用。
如乙酰胆碱受体、Gly 受体、GABA 受体、Glu 受体等 五、细胞内受体 (Intracellular Receptors):全部为DNA 结合蛋白,配体-受体复合物与特 异的DNA 顺式元件结合,调节基因表达。
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当该蛋白质复合物正常发挥作用时,它使这些受体退回到神经细胞内-在此这些受体无法接受或响应有利突触生长的信号-在合适的时间内。
When the protein complex is working properly, it moves the receptors back inside the nerve cell - where they can no longer receive and respond to the pro-growth signal - at the appropriate time.
一个受体一旦钩上了一个分子,就把那个分子固定在细胞表面,然后从那里把它摄入细胞内。
Once the receptor has seized a molecule, it binds the molecule to the cell surface from where it is taken into the cell.
该基因编码一种细胞膜受体,这种受体在细胞内信息传递中起作用,同时也在细胞分化、细胞活动性、维持正常组织结构中起作用。
The gene encodes a cell membrane receptor, which has a role in the intracellular communication, and is required for cell differentiation, cell mobility and maintenance of correct tissue structure.
Many steroid hormones act because they bind to cellulars - to receptors that are deep within the cell, often inside the nucleus.
许多类固醇激素能够起效是因为,其与存在于细胞内部的受体相结合,这类受体通常在细胞核内
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