...es share a common structural fold The core histones share a common structural fold 组蛋白的修饰 （Histone modification） • 核心组蛋白N-端尾部在核小体结构、DNA-蛋白质相互 作用中的活跃作用； • 某些氨基酸残基可被修饰，如乙酰化、甲基化、磷酸 ...
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今后，我们将在表观遗传层面对TFPI-2基因的修饰和相关组蛋白的修饰进行深入研究。
We will further investigate the relationship of histone modification and promoter methylation on the expression of TFPI-2.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
当甲基加到组蛋白后，这些基团会修饰它的性质并改变它上面特定基因的表达频率。
When methyl groups are added to a histone, they modify its properties and alter the frequency at which a particular gene is expressed.
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