histone-modifying enzymes组蛋白修饰酶 During gene transcription,it needs to recruit many histone-modifying enzymes to modify histone.
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在染色体中，SATB1还在靶基因位置上通过复活组蛋白修饰酶普遍的调节组蛋白的状态。
SATB1 also globally regulates histone status in the chromatin by recruiting histone-modifying enzymes to the target-gene loci.
这些修饰为改变染色质结构和易接近性服务，并作为转录因子或其他组蛋白修饰酶的停靠位点。
These modifications serve to alter chromatin structure and accessibility, and to act as docking sites for transcription factors or other histone modifying enzymes.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
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