肝纤维化是由于胶原纤维的产生和分解失衡,肝组织细胞外基质(ecm)过度沉积的结果。
Liver fibrosis is characterized by an abnormal hepatic accumulation of extracellular matrix (ECM) that results from both increased deposition and reduced degradation of collagen fibres.
The extracellular matrix or the collagen gel gives the tissue integrity, and in part, determines its mechanical properties.
细胞外基质或者说胶原蛋白凝胶,使组织成为一个整体,在某种程度上,决定了组织的机械性能
Extracellular matrix in most tissues is abundant in collagen and other proteins like collagen.
大部分组织中的细胞外基质,都富含胶原蛋白和其他类似蛋白
What extracellular matrix you have in any particular tissue is there because there's a balance between it being produced by one kind of cell and digested by another, and you're in this sort of state of dynamic equilibrium.
特定组织中,细胞外基质的多少,取决于一个,分泌与降解的平衡,这是一种动态的平衡关系
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