线粒体是细胞的能量工厂,其功能还涉及细胞代谢、信号传导、分化、生长、凋亡和死亡等重要过程。线粒体自噬(mitophagy)是细胞清除损伤或衰老的线粒体,并循环利用其组成元素的过程;与衰老、神经退行性疾病和癌症等诸多生理病理过程密切相关。
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结论线粒体自噬可能为组织的损伤修复提供某种分子信号,促使新的线粒体再生。
Conclusion (Mitochondrial) autophagy may release some molecular signals for wound healing so as to accelerate sufficiently the regeneration of newly formed mitochondria.
线粒体介导了死亡信号通路中自噬与凋亡的相互作用。
There is a mutual regulation between apoptosis and autophagy in death signaling process mediated by mitochondria.
自噬对于巨噬细胞清除尘粒和损伤的线粒体具有重要作用。
Autophagy plays an important role in cleaning dust particles and the injured mitochondria.
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