糖酵解的关键酶——丙酮酸激酶，如果它有遗传缺陷，就导致会atp缺乏、红细胞寿命缩短和溶血性贫血。

Inherited deficiency of pyruvate kinase, a key glycolytic enzyme, causes ATP deficiency, which leads to reduced RBC life span and hemolytic anemia.

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例如免疫介导的溶血性贫血，产生了对抗自身红细胞的抗体。

For example, in immune-mediated hemolytic anemia, antibodies are produced against the host's own RBC.

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当发生血管内溶血性贫血，更多红细胞在血液循环(血红蛋白血症)被破坏以至于超出肝球蛋白质的结合能力。

In intravascular hemolytic anemia, more RBC are destroyed in the circulation (hemoglobinemia) than can be bound to haptoglobin.

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