As a necessary structure for membrane localization and secretion of mature proteins, N-linked glycosylation plays key roles in many biological processes.
作为成熟蛋白分泌或定位于细胞膜上的必要结构，N型糖基化修饰在很多生物学过程中发挥了重要的作用。
参考来源 - 正常人尿液糖蛋白质组学研究及大肠杆菌DH5α分泌蛋白质组研究Substituted benzaldehyde or substituted phenylacetonitrile was modified by glycosyl respectively. The corresponding glycopyranoside intermediates were synthesized, and they reacted with substituted phenylacetonitrile or substituted benzaldehyde to synthesize glycosylation modified products.
对取代苯甲醛和取代苯乙腈分别进行糖基化修饰,通过相转移催化法合成相应的糖苷中间体,后者经缩合得到糖基化修饰产物。
参考来源 - 具有生物活性的芪类化合物的合成与结构修饰·2,447,543篇论文数据，部分数据来源于NoteExpress
阻断核心岩藻糖基化修饰，能有效阻断肾小管上皮细胞的EMT过程。
Blockage of core fucosylation results in the inhibition of EMT in HK-2 cells.
在糖基化工程中，通过酶法对蛋白质进行糖基化修饰和对天然糖蛋白去糖基化是研究糖蛋白结构与功能的重要手段。
In glycosylation engineering, glycoproteins are modified by glycosylation and deglycosylation. Glycosyltransferases and the enzymes of deglycosylation play important roles in the processes.
糖基化是机体蛋白质翻译后的一种重要的修饰过程。
N-glycosylation of proteins is an important post-translation modifying process in organism.
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