利用连锁不平衡进行QTL精细作图是QTL定位研究的一个新热点。
Fine mapping of QTL using linkage disequilibrium becomes more and more popular.
本发明对与腺瘤进展至腺癌细胞相关的染色体异常区域精细作图，并且提供基于其的检测方法和工具。
The present invention fine-maps the regions of chromosomal aberrations linked to progression of adenomas into adenocarcinoma cells and provides methods and tools for detection based thereon.
该方法特别适用于精细作图群体和大型突变体库的筛选鉴定，不仅通量大、速度快，而且可以确保足够的DNA浓度和纯度。
The method is suitable for large-scale mutant bank screening as well as large mapping populations with characteristics of maintaining relatively high level of DNA purity and concentration.
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