1948年，世界上第一篇随机对照研究（randomized controlled trial，RCT）在英国 发表，之后的几十年RCT被临床流行病学界认为是评价临床疗效研究的最可靠的方法，其研究结果被视...
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资料综合：14篇文章中3篇为随机对照研究，8篇为对照研究，1篇为非对照研究，1篇为荟萃分析，1篇为长期随访研究。
DATA SYNTHESIS: Of the 14 articles, 3 were randomized control studies, 8 were control studies, 1 were non-control studies, 1 was gathering analysis, and 1 was long-term follow-up study.
结果关于抗凝治疗共检索到1篇系统评价、3篇随机对照试验及8篇前瞻性队列研究；关于溶栓治疗共检索到2篇系统评价和1篇临床对照试验。
Results We found 1 systematic review, 3 RCTs and 8 prospective cohort studies about anticoagulation therapy and 2 SRs and 1 CCT about thrombolysis therapy.
然而，直到2009年第一篇关于筛查效果的有说服力的随机对照研究文章才被发表。
However, the first valid reports from randomized controlled trials on the efficacy of screening were not published until 2009.
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