等位基因突变几率预测肿瘤异质性方面低于预期,但等位基因突变几率预测等位基因特异性突变不平衡性方面则高于预期。
Lower than expected mutant allele frequency indicated tumor heterogeneity, while higher than expected mutant allele frequency indicated mutant allele-specific imbalance.
通过分析肿瘤细胞的密度及等位基因突变的几率来确定肿瘤异质性和等位基因特异性突变的不平衡性。
Tumor cellularity and mutant allele frequency were analyzed to identify tumor heterogeneity and mutant allele-specific imbalance.
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