突触前膜即突触前成分相对应的胞膜。神经元轴突末梢的分支膨大构成突触小体,突触小体膜称为突触前膜。兴奋时,突触小泡与突触前膜融合,释放神经递质。突触前膜与突触间隙、突触后膜组成突触。兴奋在两个神经元之间传递时单向的的原因:由于神经递质只存在于突触前膜的突触小泡中,只能由突触前膜释放,然后作用于突触后膜上,因此神经元之间兴奋的传递只能是单方向的。
兴奋性氨基酸转运体(EAAT)位于突触前膜、突触囊泡和神经胶质细胞膜上。
Excitatory amino acid transporters (EAAT) localizes on the presynaptic membrane, synaptic vesicle and glial membrane.
锌离子随着神经元的活动从突触前膜的囊泡中释放到突触间隙,对突触内受体进行调控。
This divalent cation is released from presynaptic vesicles into the synaptic cleft upon neuronal activity and acts as a modulator of many ligand-gated ion channels.
近年来,一种位于突触前膜、囊泡膜及神经胶质细胞膜上的糖蛋白—神经递质转运体逐渐成为神经科学界研究的热点。
Recently, transporter, that is a sort of protein located in the presynaptic membrane, vesicle membrane and glia cell membrane, has been the study hotspot of neuroscience.
When an action potential comes down this pre-synaptic axon, when it reaches this point here, it sets off the process of these vesicles dumping their content into the synaptic cleft.
当动作电位到达轴突的突触前膜时,当到达这一点时 小泡就将其内含物,排放到突触间隙中去
another thing that you'd find if you looked inside the axon terminals of any of these pre-synaptic membranes, you'd find lots of vesicles or some membrane bound compartments that contain special chemicals called neurotransmitters.
如果你仔细观察,突触前膜的轴突末梢内部,你会发现很多小泡,即膜包被的结构,包含有称为神经递质的特殊化合物
In some cells they're recycled, that is the cell is able to take up the neurotransmitter after it's released and restore it, but most often there are enzyme systems inside the pre-synaptic membrane where those neurotransmitters are synthesized.
在一些细胞中神经递质可以循环利用,这些细胞可以吸收,已经释放出的神经递质并重新储存起来,但更常见的是突触前膜中含有酶系统,在此合成神经递质
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