近年来在神经胶质瘤中发现了具有干细胞特性的肿瘤细胞,被称为神经胶质瘤干细胞(Glioma Stem Cell)。Notch信号途径是调节神经系统发育的重要信号途径之一。
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前言：目的：体外观察c6胶质瘤细胞的培养上清是否有诱导神经干细胞迁移的作用。
Objective: To study whether supernatant of C6 glioma cells can induce migration of neural stem cells in vitro.
神经干细胞和胶质瘤干细胞的研究成功，对早有定论的胶质瘤起源细胞学说发出了挑战。
Challenges have been proposed to the classical theory of origin cells of glioma, since the successful researches on neural stem cells and tumor stem cells.
本文就神经干细胞、TRAIL及神经干细胞转染TRAIL后与胶质瘤的关系作一综述。
This article will review the relationship among NSCs, TRAIL a nd glioma cells.
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