神经元和神经胶质细胞来源于同一祖细胞——神经上皮干细胞(neuroepithelial progenitor-the stem cell),分别分化为神经元约束性前体细胞(neuronrestricted precursor cell)和胶质细胞约束性前体细胞(gliarestricted precursor ce...
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目的:将神经上皮干细胞(neuroepithelial stem cells,NESCs)移植到模型鼠无神经节细胞的肠壁内,观察NESCs存活分化及对肠神经运动功能改 善的情况。
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目的:将神经上皮干细胞(neuroepithelial stem cells,NESCs)移植到模型鼠无神经节细胞的肠壁内,观察NESCs存活分化及对肠神经运动功能改 善的情况。
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方法利用无血清悬浮培养、单细胞克隆技术分离神经上皮干细胞;
Methods Serum free cells suspension culture and single cell cloning technique were used to isolate neuroepithelial stem cells.
目的从胚胎大鼠脊髓神经管中分离神经上皮干细胞并诱导其向多巴胺能神经元方向分化。
Objective to isolate neuroepithelial stem cells from the spinal cord neural tube of the embryonic rat and induce them to differentiate into dopaminergic neurons.
结论:胚胎神经上皮细胞多数为神经干细胞,黑质内移植后可以存活并分化为多巴胺能神经元。
Conclusion: Present findings demonstrate that embryonic neural stem cells dissociated from neural tube can survive and differentiate into dopamine neurons.
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