方法采用全细胞膜片钳技术在急性分离的大鼠背根神经节细胞上观察龙血素B对辣椒素诱发的辣椒素受体电流的影响。

Methods In acutely isolated rat DRG neurons, effects of loureirin B on capsaicin-evoked currents were observed using whole-cell patch-clamp technique.

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辣椒素是香草酸(vanilloid)分子家族的成员之一，它会与舌头上香草酸受体1亚型(vanilloid receptor subtype 1)结合。

Since capsaicin is a member of the vanilloid family of molecules, it binds to a receptor on the tongue called the vanilloid receptor subtype 1.

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但是奇怪的是VR1受体并不是专门用来检测辣椒素的，它们只和辣椒素结合只是偶然发生的。

But here's the strange part: VR1 receptors weren't designed to detect capsaicin. They bind spicy food by accident.

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