在NOS1基因启动子区鉴定了两个正调控区域和两个负调控区域，同时TS A可上调不同长度启动子的转录活性。
Two positive regulation regions and two negative regulation regions were found within NOS1 promoter. TSA may up-regulate the transcription activities of NOS1 promoters of different length.
1985年Aaron先生发现了一类具有与转录因子类似功能的新的蛋白；该蛋白能够识别特定的DNA区域并且结合上去，从而导致基因活性上升或者下降。
In 1985 Sir Aaron discovered a new class of proteins that mimic this function and can recognise specific stretches of DNA and bind to them, boosting the activity of genes or damping them down.
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