研究氧化型低密度脂蛋白对小鼠腹腔巨噬细胞胆固醇蓄积的影响,并探讨其与组织蛋白酶活性之间的关系。
Aim to explore the effect of oxidized low density lipoprotein (ox LDL) on cholesterol accumulation in mouse peritoneal macrophages and its relationship with activity of lysosomal cathepsin.
结论HP感染可引起脂代谢紊乱,可能机制为HP感染抑制了脂蛋白酶的活性与分泌。
Conclusion HP infection might cause disorder in the lipid metabolism. The possible mechanism might be that the HP infection can suppress activity and secretion of lipoprotein lipase.
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